22,601 research outputs found

    Keener\u27s Spirit hermeneutics: Reading scripture in the light of Pentecost (Book Review)

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    A review of Keener, C. S. (2016). Spirit hermeneutics: Reading scripture in the light of Pentecost. Grand Rapids, MI: Wm. B. Eerdmans. 522 pp. ISBN 978080287439

    Wilder, Brand, Chester, Osborne, and Seifrid\u27s Perspectives on Our Struggle with Sin: Three Views of Romans 7 (Book Review)

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    A Review of Perspectives on Our Struggle with Sin: Three Views of Romans 7, By Terry L. Wilder, Chad Brand, Stephen Chester, Grant R. Osborne, and Mark Seifrid. Nashville, TN: B&H Academic, 2011. 213 pp. $24.99. ISBN 9780805447910

    Spine Biomechanics Associated with the Shortened, Modern One-Plane Golf Swing

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    The purpose of this study was to compare kinetic, kinematic, and performance variables associated with full and shortened modern backswings in a skilled group of modern swing (one-plane) golfers. Shortening the modern golf backswing is proposed to reduce vertebral spine stress, but supporting evidence is lacking and performance implications are unknown. Thirteen male golfers performed ten swings of each swing type using their own 7-iron club. Biomechanical-dependent variables included the X-Factor kinematic data and spine kinetics. Performance-related dependent variables included club head velocity (CHV), shot distance, and accuracy (distance from the target line). Data were analysed with repeated measures ANOVA with an a priori alpha of 0.05 (SPSS 22.0, IBM, Armonk, NY, USA). We found significant reductions for the X-Factor (p \u3c 0.05) between the full and shortened swings. The shortened swing condition ameliorated vertebral compression force from 7.6 ± 1.4 to 7.0 ± 1.7 N (normalised to body weight, p = 0.01) and significantly reduced CHV (p \u3c 0.05) by ~2 m/s with concomitant shot distance diminution by ~10 m (p \u3c 0.05). Further research is necessary to examine the applicability of a shortened swing for golfers with low back pain

    CO2-dependent opening of an inwardly rectifying K+ channel

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    CO2 chemosensing is a vital function for the maintenance of life that helps to control acid–base balance. Most studies have reported that CO2 is measured via its proxy, pH. Here we report an inwardly rectifying channel, in outside-out excised patches from HeLa cells that was sensitive to modest changes in PCO2 under conditions of constant extracellular pH. As PCO2 increased, the open probability of the channel increased. The single-channel currents had a conductance of 6.7 pS and a reversal potential of –70 mV, which lay between the K+ and Cl– equilibrium potentials. This reversal potential was shifted by +61 mV following a tenfold increase in extracellular [K+] but was insensitive to variations of extracellular [Cl–]. The single-channel conductance increased with extracellular [K+]. We propose that this channel is a member of the Kir family. In addition to this K+ channel, we found that many of the excised patches also contained a conductance carried via a Cl–-selective channel. This CO2-sensitive Kir channel may hyperpolarize excitable cells and provides a potential mechanism for CO2-dependent inhibition during hypercapnia
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